CHM 202 - Organic Chemistry 2

 
Description
This course is the second semester of a two-semester course in organic chemistry. The emphasis is put on organic spectroscopy, multi-step organic synthesis and reaction mechanisms. Spectroscopy topics discussed include Mass Spectrometry, Infrared (IR) Spectroscopy and Nuclear Magnetic Resonance (NMR) Spectrometry.  The course explores the nomenclature, physical properties, synthesis and reactions of several carbonyl functional groups and carboxylic acid derivatives. The nucleophilic addition, α-substitution and condensation reactions of carbonyl compounds as well as the nucleophilic acyl substitution reactions of acid chlorides, anhydrides, esters and amides are discussed. In the final part, the course surveys biologically relevant compounds such as amines, carbohydrates, amino acids, peptides and proteins.  The laboratory component of the course focuses on the synthesis, isolation and characterization of small organic compounds utilizing the reactions learned in the lecture.

1. Interconvert between the names and structures of the organic compounds with the different functional groups (dienes, aromatic, carboxylic acids, acid derivatives, aldehydes, ketones, amines, carbohydrates, lipids and amino acids).
2. Correlate the bonding and structure to the reactivity pattern of given organic molecules.
3. Generate reasonable reaction mechanisms for given organic reactions utilizing curved arrow notation.
4. Predict the major products of organic reactions on the basis of the reaction mechanism.
5. Apply reactions to multi-step organic syntheses.
6. Compare and contrast structure-property relationships between biologically relevant molecules such as carbohydrates, lipids, amino acids, peptides and proteins.
7. Demonstrate proficiency in organic laboratory skills enabling synthesis and isolation of organic compounds.
8. Examine experimentally the properties of organic molecules delineating them in the laboratory report.

 Listed Topics

1. Mass spectrometry
2. UV and IR spectrometry
3. NMR spectrometry
4. Benzene, aromatics and electrophilic aromatic substitution
5. Organometallic reagents
6. Oxidation and reduction reactions of carbonyl compounds
7. Synthesis and reactions of carboxylic acids and their derivatives
8. Substitution and condensation reactions of carbonyl compounds
9. Amines
10. Carbohydrates
11. Lipids
12. Amino acids, peptides and proteins.

• Critical Thinking & Problem Solving
• Quantitative & Scientific Reasoning

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